Ciak Posted January 15, 2021 Share Posted January 15, 2021 Hey everyone... I am desperate! Can someone help me with the synthesis of COOHCH2NHCH3 from CH2CH2? Link to comment Share on other sites More sharing options...
chenbeier Posted January 15, 2021 Share Posted January 15, 2021 (edited) CH2CH2 => HO-CH2CH2Cl => ClCH2COOH => ClCH2COOCH3 => CH3NHCH2COOCH3 => CH3NHCH2COOH Edited January 15, 2021 by chenbeier Link to comment Share on other sites More sharing options...
Ciak Posted January 15, 2021 Author Share Posted January 15, 2021 At the stage when Ch3NH2 react with ClCH2COOCH3 i think we will have a mixure of 1o,2o,3o amines and we wont be able to get the one product i want.. is there any other way including the reaction of RCOCL+ RNH2? Link to comment Share on other sites More sharing options...
chenbeier Posted January 15, 2021 Share Posted January 15, 2021 Maybe can use Strecker Amino acid synthesis. Link to comment Share on other sites More sharing options...
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