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Question about Gastroenterology


Anchovyforestbane

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1 hour ago, BabcockHall said:

Is this homework?

It certainly may help with homework, but I wouldn't say that is the purpose. I'm intensely interested in the sciences, is all. 
Now that you mention it though, it does appear to have been moved to the Homework Help category. I'm not really sure why that happened. 

 

 

1 hour ago, BabcockHall said:

 Do you know anything about membrane-bound transporters?  These are proteins that have certain specificities for things like glucose and other metabolites.

I'm not sure if you mean carrier/channel transport proteins, vesicular proteins, or something else with which I'm unfamiliar. In the case of either of the first two, don't those act on a subcellular scale? Is it a chain of protein transportation that extends beyond the microvilli's absorption sites? If so, how specifically is it structured, and how does it work biochemically?

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I mean transporters that reside in the plasma membrane itself.  For example there is a family of glucose transporters (GLUTn, where n = 1, 2,...) that facilitate the diffusion of glucose across plasma membranes.  Chapter 11 in Nelson and Cox's principles of biochemistry textbook has a good discussion at the advanced undergraduate level.

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28 minutes ago, BabcockHall said:

I mean transporters that reside in the plasma membrane itself.  For example there is a family of glucose transporters (GLUTn, where n = 1, 2,...) that facilitate the diffusion of glucose across plasma membranes.  Chapter 11 in Nelson and Cox's principles of biochemistry textbook has a good discussion at the advanced undergraduate level.

So, carrier/channel transport. What specifically are the structures and mechanisms between the microvilli and bloodstream which carry out this chain diffusion?

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Ah, that is more of a physiological question, and I don't know much in that area.  With respect to the glucose transporter family, they are not engaged in active transport.  On the other hand, glucose transport into the cell from the intestinal lumen is accomplished via active transport.

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