Syda Posted October 30, 2020 Share Posted October 30, 2020 I am learning about cre-loxp recently at this is all new to me. I want to have a mouse strain that will have a tissue specific knockout of a certain gene. Is there a way to introduce a reporter in that same tissue? For example, if I have a liver specific cre and I want the liver tissue to express lacz after knocking out the mitochondrial transcription factor from liver cells with floxed strains, what should be my approach? Link to comment Share on other sites More sharing options...
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