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T-cell responses following COVID-19


CharonY

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T cell responses (especially T helper cells CD4) are an important element of the immune memory. A few studies have now found that convalescent folks with mild or no symptoms show detectable T cell responses, which is positive news.

(Sekine et al. 2020 Cell (preproof); biorxiv: https://www.biorxiv.org/content/10.1101/2020.05.26.115832v1).

 

A couple of other preliminary studies seem to suggest that even antibody responses may be present for longer than previously anticipated (e.g. https://www.medrxiv.org/content/10.1101/2020.08.01.20166553v1, https://www.medrxiv.org/content/10.1101/2020.08.11.20171843v2) .

So we are seeing an increasing number of studies that suggest that responses are at least detectable for about 3 months. Obviously, we only know the full scope way later, but at least there is more evidence that vaccination might turn out to be be a viable strategy.

 

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1 hour ago, MigL said:

Good news.

Looking forward to normal life again.
( haven't been hugged in quite a while, and I need one )

I think this ongoing pandemic is going to be an interesting lesson for how we do things in the future. One is that we just go back and do things as usual. Here, I a fear that we will (again) become complacent until the next pandemic happens within, say, 5-20 years.

The other is that at least some things may change permanently, as it already has happened in some countries to various degrees in the past, such as more common use of facemasks, re-thinking of hand hygiene and so on. As whole I think this test run has shown many deficiencies, including the fact that warnings are generally ignored until it is too late. On the positive side I have never seen such a massive engagement of the global research community to tackle an issue from all kind of fronts. 

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