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pegasus10

Muscle glycogen phoshporylase

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Hello, is muscle glycogen phosphorylase sensitive to glucose? I mean, is glucose an allosteric effector for the muscle isoform of glycogen phosphorylase? My answer would be no, but going through Voet's Biochemistry book I found a diagram in which glucose is depicted as a negative allosteric effector for glycogen phosphorylase in general, without specifying muscle isoform / liver isoform.

Thanks in advance! 

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Nelson and Cox, Figure 15-38 also talk about liver glycogen phosphorylase as a sensor of glucose.  I suspect that it is only in liver, but I am not certain.  Any luck with a PubMed search?

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