Jump to content

Why can't natural killer cells target cancer cells?


8link48
 Share

Recommended Posts

I don't know whether or not I'm in the right topic, but I'd like to know why we can't try to create a mutation in natural killer cells to target cancer cells within the human body. If it is possible is there any chance you could describe the process?

Link to comment
Share on other sites

We will be able to do that soon with most cancers.

We already have CAR T in use https://www.cancer.gov/about-cancer/treatment/research/car-t-cells

We also have drugs like Ipilimumab and Pembrolizumab that "force" the immune system to attack cancer cells. A combination of Ipilimumab and Nivolumab wuadrupled 5 year survival for metadtatic melanoma

 

Link to comment
Share on other sites

On 12/8/2018 at 4:04 AM, Hans de Vries said:

We will be able to do that soon with most cancers.

We already have CAR T in use https://www.cancer.gov/about-cancer/treatment/research/car-t-cells

We also have drugs like Ipilimumab and Pembrolizumab that "force" the immune system to attack cancer cells. A combination of Ipilimumab and Nivolumab wuadrupled 5 year survival for metadtatic melanoma

 

This is off topic to the OP, since your cited approach is engineered adaptive immunity. NK cells are part of the innate immune system and are activated by cytokines or interferons = no antibodies involved.

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share

×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.