Keysi Posted May 7, 2018 Share Posted May 7, 2018 (edited) Hi, I'm trying to work out how the cell removes and recycles proteins in the cell membrane, such as ion channels. I think it'll be by 'digestion' by lysosomes, but I spent hours last night searching for the actual mechanism/process by which they are physically removed from the membrane when the time comes, and I couldn't find anything. Even just a point in the right direction to the name of the process or a website with the info, rather than the answer would be greatly appreciated. Thanks guys. EDIT- the closest I have figured so far would be crinophagy, but I'm not sure if that is exactly right. Edited May 7, 2018 by Keysi Link to comment Share on other sites More sharing options...
CharonY Posted May 8, 2018 Share Posted May 8, 2018 Protein-turnover at membranes is fairly complex and there are quite a few different pathways, depending on the targets and e.g. whether they are bound for recycling or further degradation. However, the best understood degradation mechanism is the ER-associated degradation pathway, Link to comment Share on other sites More sharing options...
Keysi Posted May 10, 2018 Author Share Posted May 10, 2018 Cool, thanks for the reply. Link to comment Share on other sites More sharing options...
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