Jump to content

Grignard reaction vs Aldol reaction


adianadiadi

Recommended Posts

We know that Grignard reagent is strongly basic. It is stronger than NaOH.  

We also know that sodium hydroxide is just enough to abstract a proton from active methyl group of acetaldehyde to carry out aldol reaction.

Now my point is, if we use Grignard reagent, acetaldehyde should undergo aldol reaction instead of Grignard reaction.

Any comments?

Link to comment
Share on other sites

18 hours ago, adianadiadi said:

Now my point is, if we use Grignard reagent, acetaldehyde should undergo aldol reaction instead of Grignard reaction.

Clearly, no it "shouldn't", or it would.

It seems that the aldol reaction is faster.

Or maybe the proton transfer is fast, but effectively reversible.

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.