Jump to content

Does gene therapy affect non-patients that are in contact witth the patient?


Damian

Recommended Posts

Not a subject I know much about but I did a quick search and it doesn't look as if contagion is a significant risk factor. I'm not sure why. Presumably they choose vectors which are not easily transmitted (or are modified to be less easily transmitted).

 

For example, this review of the risks only has a passing mention of contagion: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC543871/

Edited by Strange
Link to comment
Share on other sites

It depends on the vector - each will have it's own risk assessment and treatment will proceed based on those risks. I've only ever worked with very low risk vectors (fowlpox with no replicative ability) and extra advice to patients was no swimming and avoid babies and both of those were entirely precautionary with no specific rationale for them.

 

The company supplying the drug have to supply a document like this for the risk assessment.

Link to comment
Share on other sites

It depends on the vector - each will have it's own risk assessment and treatment will proceed based on those risks. I've only ever worked with very low risk vectors (fowlpox with no replicative ability) and extra advice to patients was no swimming and avoid babies and both of those were entirely precautionary with no specific rationale for them.

 

The company supplying the drug have to supply a document like this for the risk assessment.

And, does the clinical approved tratments (like cystic fibrosis) use low risk vectors?

Link to comment
Share on other sites

  • 2 months later...

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.