Endy0816
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Posts posted by Endy0816
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22 hours ago, CharonY said:
It is not working the way you think. The issue here is not exposure of DNA to external factors, they will have that all the time, anyway as active regions have to be unwound (most of the time far from the ends where the telomeres sit). Rather, they are involved in solving the end of replication issue (which is not the subject here) but also interacting with our own damage response system. The issue is really is focused on the end of chromosomes. If we have DNA damage, our response pathways either try to fix it or it can lead to further degradation pathways, which ultimately can result in cell arrest or death. To prevent that, telomeres together with a protein complex called sheltering. There are different functions involved, but ultimately they stop a number of different pathways that are involved in DNA repair pathways (specifically nonhomologous end joining and homology directed repair, in case you want to read up) as well as signaling pathways that are activated when DNA breaks are detected (ATR and ATM).
So in short, the resulting structures are not so much about exogenous damage protection, but really about protecting our ends from our repair systems.
Edit: I found an article on wiki that explains it a bit: https://en.wikipedia.org/wiki/Shelterin
The shift from circular to linear DNA must have involved some really unique circumstances.
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Found this:
QuoteFungus-growing termites cultivate monocultures of a specific fungi (of a genus called Termitomyces) for food in their colony, analogously to human farmers growing crops. The termites forage for dead plant material in the environment, bring this into the mound and provide it to the fungus as a growth substrate. After fungal growth, the termites use the mixture of fungus and degraded plant material and also the asexual spores produced by the fungus as food. They also use the spores to inoculate new fungus gardens.
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1 hour ago, raphaelh42 said:
hello,
i'm asking myself why someone would vote for a president that anyway will have thousands/million of votes (+1 is insignificant in this case IMO)
same about someone leaving a like on a youtube video that already have thousands.
is that part of what we call "union" ? or it's just a weakness that you practice to feel less small, more important ?
how do we call this phenomenon ?
If you don't vote you can't complain afterward.
Sometimes single vote can make all the difference too.
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3 hours ago, sethoflagos said:
Draw your own conclusions as to the attitude of private enterprise to the health and well-being of its customers.
Yeah externalities are a big issue.
If impact doesn't cost the company anything it has no reason to care.
Dioxin is nasty. We had to demolish a whole Town because of that stuff.
https://www.history.com/this-day-in-history/road-contamination-prompts-evacuation-of-town
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Really I think the government should have a controlling stake in anything vital.
Free market may or may not result in better efficiencies, but that's no good if the country goes under in the persuit of short term profits.
Half the time Utilities are a natural monopoly anyways.
https://en.m.wikipedia.org/wiki/Natural_monopoly
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On 9/14/2022 at 10:42 AM, dimreepr said:
It's always struck me that an unrestricted/unregulated version of capitalism, is a rather silly way to ensure one's future...
Feel free to ask me why, the answer is...
For sure.
My own Utilities provider is owned by the city which I think is a better model.
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11 hours ago, Ned said:
I do not know who wrote the link you provided but it is very contradictory and does not seem an accurate account .
From my understanding space-time is any mathematical model that uses the 4 dimensions of xyzt . Space-time having nothing to do with a ''fabric'' ?
Can anyone provide evidence that the underlying space can in anyway change other than hearsay ?
Can anyone explain why somebody has fabricated a variation version of expansion without proof that doesn't conform to conventional expansion physics ?
A Hilbert space or perhaps a Higgs field could expand or grow but I can't see how an underlying space that isn't matter or energy could do anything . It is my personal opinion that Newton was correct about absolute space and the immovable nature of space but I also think that Einstein was correct too . If we consider that a Hilbert space or a Higgs field in being ''fused'' with space and indistinguishable from space in appearance, then this allows for space-time curvature and expansion . However , it isn't the underlying space that curves or expands but rather instead , it is the substance that is ''fused'' with space . The problem is though , any of the mentioned could be viewed as an aether which we are unable to detect presently ! Additionally in considering any sort of spatial ''fabric'' , we'd have to consider the laws of conservation of space , asking the question does space have the potential to conserve an amount of energy.
Newton was wrong about that. Only human.
Our Satellites can require that their clocks be corrected due to a different amount of time passing for them than for us.
It isn't intuitive, but our intuition is impacted by the environment we're used to.
Anyways your question was about the size of the Universe. Is there anything else in regards?
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3 hours ago, Ned said:
Isn't 93 billion light years just a length between visible sources ?
You say the spacial size of the entire Universe is unknown , which I think I will have to agree with . Is there any specific math that can describe the unknown size of the Universe ?
What do you mean by spacial expansion ? Do you mean the diameter between visible sources is increasing that expands the measure of space between points or do you mean something else ?
Think this explains it better than I can:
https://www.cs.mcgill.ca/~rwest/wikispeedia/wpcd/wp/m/Metric_expansion_of_space.htm
My attempt...
Where gravity is really really really weak(well outside any galaxy) you can end up with spacial expansion.
Distance between what could be considered otherwise stationary points on a graph, ends up growing.
Photons of light take longer to reach us from these areas and well have traveled further as a result.
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Yeah we're essentially waiting for the light itself to reach us, so can only see out so far.
With spacial expansion though this value is a bit more than c*t might strictly suggest.
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2 hours ago, StringJunky said:
Why does, it seems, everything have to go to court before a legislature can execute policy in the US? It seems to me the Judges are more powerful than the politicians and it's they, due to their accepted expressed political bias, de facto run the country?
Doesn't have to, but Groups or individuals will often challenge some bit of legislation.
They're all elected or appointed by someone elected though.
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1 hour ago, StringJunky said:
In her last public photo she looked just like anybody's grandma, I thought, like, finally she'd done away with her usual deportment and facial control. She was just herself... a smiling old lady. A fitting final image.
Definitely.
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12 hours ago, MigL said:
A rant, with few solutions offered, but kind of funny ( if you don't live there ), and probably spot on.
So why are these people not getting voted out of office ?
edit : This Jonathan Pie guy is hilarious.
Just watched his 'tribute' to Boris JohnsonAgain, why are thesepeople getting elected ?
( at least the Americans had the common sense to get rid of D Trump, although he doesn't seem to get the hint )They can't.
Their next scheduled general election isn't until 2025.
The ruling party(Tories) have been using the media to great effect for awhile though. Largely demonizing opponents and blaming others for the effects of their own extreme laissez-faire economic and social policies.
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1 hour ago, mistermack said:
I've just seen a repeat of a satire show, done just before the invasion.
Boris Johnson said there would be "significant consequences" and Liz Truss (next PM) said there would be a "severe cost".
How right they were. They didn't say that the cost would be for us, not Putin though.
I also read elsewhere that Olaf Scholz went to see Zelenskyy just weeks before, and asked him to abandon the intention of joining NATO to avoid invasion. Zelenskyy turned him down flat.
Does anybody still think he's a wise and gracious leader, who's guiding his country down the best available path?
'Better to reign in Hell than serve in Heaven.'
...and considering how even many Russian notables suffer mysterious accidents, perhaps one wouldn't be serving all that long either.
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Ultimately going to be rooted in culture. Often see a version of the modern or historical British political system in works by British authors for the same reason.
Niven does have a number of works outside of or only tangentially related to the Man-Kzin War series.
Thought Ringworld series was particularly good alongside Integral Trees. The larger conflict is often simply a backdrop for the interspecies or human interactions.
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3 hours ago, Saleque Ahmed said:
Time is a dimension that always moves forward, never backwards. But as we move closer to the black hole, time first turns 45% and then 90% and time changes its axis. The question is where does the time go?
That would be past the Event Horizon.
My understanding is that our dimensions would swap. Time for Space.
If memory serves, The Universe and Dr. Einstein gives a pretty good overview:
https://www.amazon.com/Universe-Dr-Einstein-Lincoln-Barnett/dp/0486445194
I like to visualize the dimension of time as a road we're traveling along. We're stuck traveling along it so as a result we observe time as always advancing(odometer ticking up). Not necessarily the same as what time itself is doing.
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Thought I'd post these up. Pretty cool the images it can create for you. Tried to push it to see something that it couldn't have existing images of to see what it could come up with(Modern day Atlantis, Alien, Futuristic, Most Popular X in Year 3000).
In some case it would incorporate an interpretation of the text prompt too.
ie. Futuristic Bible, Alien School, Alien Religious Service
which thought was interesting too.
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4 hours ago, paulsutton said:
Fingers crossed for Friday, It does seem that what there will be a briefing later but this is part of the journey eh.
Same.
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15 hours ago, paulsutton said:
Mission attempt on 29th August scrubbed : https://blogs.nasa.gov/artemis/2022/08/29/launch-attempt-scrubbed/
Yeah hoping to see it. Like seeing the NASA launches.
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3 minutes ago, mistermack said:
Seems like a lot of distraction tactics to me.
The taxpayer funds trains, bin collections, barristers, all sorts. The unions seem to regard them as cash cows, ready for milking.
If you want the lower paid to get more money, stop allowing virtually unrestricted immigration of unskilled labour. The reality of the figures doesn't match the "get tough" public stance. Rwanda was always a distraction. They knew perfectly well that it was a non-runner. It's just done to look tough, while the numbers remain huge.
So long as there is a regular inflow, the market price for less skilled people will remain depressed.
Even skilled positions are underpaid.
In our own history, trying to fight against migrant waves has never really worked. We certainly don't have it all figured out either though.
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39 minutes ago, mistermack said:
Agreed. And that leaves society wide open to blackmail by strike. That's why I would introduce compulsory no-strike contracts for vital services. It already happens for some services. I say it should be much more widespread. The employment market should decide the level of the wages.
I think that's a question-dodging red herring.
Would you sign such a contract knowing your pay isn't likely to keep up with the cost of living?
Just a statement of facts.
Rwanda: 120 million for 200 migrants
Oneweb: 500 million
Marble Arch Mound: A low 6 million
The UK seems pretty well off.
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19 minutes ago, mistermack said:
That's fine, if you want to pay double the tax. And the workers are tax payers too, you know.
When you have a cost of living spike, like now, if everybody got a rise to cover it, the cost of living rises furthur. There is no magic money tree. If the inflation is coming from abroad, as in the current case, then a country simply can not defeat it with their own wage rises. Do that, and your currency falls, and you stoke more inflation, and your wage rise is worthless within months. Rampant inflation can even lead to world wars. It's a horrific thing.
It takes off, it has a life of its own. People see one lot getting a big rise, and demand the same or more. It's like lighting a fire. Governments have to print more money, and you end up carting it round in wheelbarrows.
If prices rise, you can pay it or don't buy it. It's only when people stop buying, that inflation falls. Why should the tax payer cover the price rises for bin men, when they are having to pay the same price rises themselves?
Sometimes the work being done is so vital that you simply have to pay. Society comes to a stop otherwise.
Raising wages also need not mean raising taxes necessarily. Lot of UK's tax revenue is being spent on extravagant projects.
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Not a really free market situation. These are mostly government funded jobs with wages/QOL below where they should be(about half).
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6 minutes ago, mistermack said:
If there was a genuine market for labour, as there is for everything else, then the market would decide the pay levels. If you can't recruit bin men, then by all means pay them a rate that will attract more applicants.
That's not what's happening now. The bin men have their jobs, but refuse to do it. So basically they blackmail the public for more money with their closed shop.
I haven't heard of a shortage of applicants. If there were, then the wage demands would make sense.
Not necessarily.
If you have a Monospony you can supress wages.
https://www.economicshelp.org/labour-markets/monopsony/
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Lot of overlap with others
Island of the Blue Dolphins, Brave New world, To Kill a Mockingbird, The Good Earth, Siddhartha, Of Mice and Men, The Garden of forking Paths, The Awakening, Lord of the Flies, The Great Gatsby, Animal Farm, 1984, Night
Science fiction and Fantasy recreationally.
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HTML
in Computer Science
Posted
Technically combined with CSS you can implement some logic. You're better off using it as originally intended though.
Much better for any eventual debugging and/or reusing code.