jimmydasaint

Good effort mate. You put your time and effort into this. It is difficult to avoid copyright issues. Why not just link to other sites.

Can't recall any past life and how accurate is the apparent data about past lives. Are people completely accurate with historical details?

Excellent and detailed answer. Just what I wanted. Thanks for that. OK, next step, the virus needs enzymes, I presume to assemble the protein coat or to prepare its genetic material. How would it sound to flood the body with enzyme inhibitors which are inside liposomes (membrane bubbles) which are specific to virally infected cells. The enzyme inhibitors are attached to a cyanide or poisonous chemical which is only activated when the attachment to the enzyme occurs. The virally infected cells are destroyed specifically. I realise there are extra problems here but I am just starting again.

I find the attacks on iNow absolutely unacceptable and personal and will not now contribute to this thread. I advise all sensible persons to do the same.

Due to the details of the experiments involved and the sheer breadth of material I had to include, 210 pages. I managed to get five peer-reviewed papers out of my material though so I'm not complaining.

I don't think my thoughts are controlled. However it may be more accurate to say that our communications and website use are carefully monitored and the time may arise when thoughts could be read using Terahertz technology. I am in touch with people who claim to be affected by such technologies as lab rats. It is quite frightening.

I guess if you don't know what an ion is you don't understand the basics.

1) All solids, liquids and gases are made of atoms.

2)These atoms are seen in the Periodic Table.

3) If you look at any single atom, e.g. potassium, it contains a middle bit which is positive and has negative bits circulating it.

4) The middle bit, called a nucleus has positive protons, the negative bits are called electrons.

5) The nucleus also has neutrons without a charge which may be holding protons together because of the repulsion caused by the positive charges pushed together in a small space.

6) In any atom (not ions), the number of protons and electrons must be the same to balance each other out.

7) Nobel gases seem to be pretty stable and contain 8 electrons in their outer shell.

8) Go figure how many electrons a potassium atom must lose to become a charged particle called an ion?

The paper seems to point to an induction of LTP with a "cAMP/p38 MAP kinase-dependent signaling cascade". Can we apply this study to humans without becoming proto-eugenicists?

OK guys and I don't know if I am making much sense here, why can't we flood the body with 'self' viral receptors which are engineered to bind irreversibly to the viruses. During an infection so that there is no antibody response against 'self' but virus particles who leave a cell to invade others become 'distracted' by the receptors around them and the scope of the infection is localised and mitigated.

Why don't we flood the body with artificial virus receptors We can then make antibodies against the virus receptors and so the antibodies would block the virus from getting into the cell - like locking a door and breaking the key off in the door so that no one can get in? I am not a virologist.

Horses for courses surely. What about mind maps, concept maps which use colour and imagery? My best students, some of which went to Oxford and Cambridge loved to make lists. They hated mind mapping and mnemonics.

I assume they would also use a Western blot with a specific anti-immunoglobulin produced as monoclonal antibodies (so they would be more specific). There is a method used here which could be easily copied:

Characterization of Proteins Produced by Virally Infected

Cells. Total cellular lysates and supernatants were subjected

to SDS/PAGE according to Laemmli (23). For studies involving

the intrinsic [35S]methionine labeling of cellular proteins,

1 ,uCi (1 Ci = 37 GBq) of [35S]methionine was added to

previously methionine-starved cells and incubated for 4 hr.

Acrylamide gels were dried, and autoradiograms were produced,

typically in 30-min exposures using Kodak XAR film

and Kronex (DuPont) intensifying screens. Western blot

analysis was carried out essentially as described (24), with an

1251I-labeled affinity-purified goat anti-mouse IgG antiserum

http://www.pnas.org/content/87/10/3942.full.pdf

In a Seminar, a young and pretty female scientist answers a question from a member of the audience: "I think you are wrong there, J____ et al mentioned that there was very little lectin activity in their paper..."

Answer from the member of the audience: "No, I think you are wrong - I am J_____ ...".

At this point the audience collapses in helpless laughter (I managed to hold in my laughter).

I hope this helps. It is good old wiki:

http://en.wikipedia.org/wiki/Blood_type

Has anyone remembered by smell? I mean - has anyone used aromatherapy oils to associate smell with learning a topic or two. I would be interested in trying this out.

I don't know about viruses being borderline. They have genetic information protected from enzymatic degradation and seem to have found a way to propagate themselves from generation to generation quite well. If that isn't alive, I would be surprised.

I used to ask complicated questions at Seminars during my PhD and couple of post-docs. However, the humiliation was on me - I was doing it to satisfy my ego and to show how clever I thought I was. In my teaching, I am humbled by the amazing complication of the few pounds of grey matter we have in our skulls.

I love this stuff. Apparently Cecil Rhodes, the great industrial pirate said with regret upon his deathbed the following words:

"So little done, so much to do." Rhodes, Cecil John (1853-1902)

According to an unflattering T.V. series about Rhodes, his actual last words were: " Turn me over, Jack." Hardly memorable...

I also love this one although it could hardly be called famous:

"Why yes, a bullet-proof vest!"

(Last request before the firing squad.)

Rodgers, James W. ( -1960) [American criminal]

Thanks for the answer guys. That is, assuming that Black Holes really exist? I remember reading something confusing suggesting that they don't exist but cannot find the reference.

This, and the fact that I was reading about the Voyager Missions, prompted me to think why send Voyagers out on either side of the ecliptic but neglect to look at the Black Holes which are apparently at the centre of each galaxy to help galaxies to form in the first place.

http://news.bbc.co.uk/2/hi/science/nature/7774287.stm

You can't pass information out of a black hole. But there is noting to stop you going to take a look personally, if you are really curious (other than the fact that you would be pulled apart by the gravity of course).

Thanks for the offer. I 'll give it a miss. My wife would not forgive me if I went into suspended animation for a thousand years - she would find a way to get at me somehow - regardless of the time or place

Thanks for the replies guys. The dome would have a protective function to support the correct types of organisms and , if successful could be grown larger in size. Thanks for the mention of algae and archeons which can survive in extreme conditions. I was hoping that there could be a possibility of independent growth of organisms which could make a subtle change to the atmosphere. Seems unlikely though.

However, I was coming from the viewpoint that the Earth was also similarly seemingly inert but changed to accommodate large amounts of oxygen.

npts2020 - this is what I was referring to because I though the Earth's atmosphere was changed by photoautotrophs to produce oxygen:

First Atmosphere

 

Composition - Probably H2, He

These gases are relatively rare on Earth compared to other places in the universe and were probably lost to space early in Earth's history because

Earth's gravity is not strong enough to hold lighter gases

Earth still did not have a differentiated core (solid inner/liquid outer core) which creates Earth's magnetic field (magnetosphere = Van Allen Belt) which deflects solar winds.

Once the core differentiated the heavier gases could be retained

Second Atmosphere

 

Produced by volcanic out gassing.

 

Gases produced were probably similar to those created by modern volcanoes (H2O, CO2, SO2, CO, S2, Cl2, N2, H2) and NH3 (ammonia) and CH4 (methane)

No free O2 at this time (not found in volcanic gases).

Ocean Formation - As the Earth cooled, H2O produced by out gassing could exist as liquid in the Early Archean, allowing oceans to form.

Evidence - pillow basalts, deep marine seds in greenstone belts.

http://www.ux1.eiu.edu/~cfjps/1400/atmos_origin.html

Very simple question. Why can't NASA or other space agencies around the world send a Voyager-type space craft straight into a Black Hole to broadcast information right up to the point it is obliterated? Or are there problems associated with this question because it is an experiment that does not seem to have been performed yet?

Just musing about the Earth's early atmosphere as being mostly carbon dioxide and then slowly being converted into substantial amounts of oxygen from photoautotrophs.

I just wonder if the original conditions for the transformation of the Martian atmosphere can be re-created as an evolutionary experiment and then periodically seeded with further and further species until levels of oxygen are created. I would envisage a dome-like structure to protect the bacteria or protists from the harshness of the Martian atmospheres.

Any views on this?

MedGen, they are intelligent questions. Do you mean that you are looking for less associations of haplotype and disease than these strong correlations in this reference which looks at Ashkenazi Jewish patients and that that these confounding factors can be taken into account? Just trying to clarify what you meant...

Of 26 Ashkenazi Jewish patients with pemphigus vulgaris, 24 (92.3%) carried the major histocompatibility complex (MHC) class II alleles HLA-DR4, DQw3, of which all were of the subtype DR4, DQw8. From studies of the patients and their families, haplotypes were defined. It was found that, of the patients who carried HLA-DR4, DQw8, 75% carried one or the other (and in one case, both) of two haplotypes [HLA-B38, SC21, DR4] or HLA-B35, SC31, DR4. The former is a known extended haplotype among normal Jews, with a frequency of 0.102, and the latter may also be an extended haplotype in this ethnic group, with a frequency of 0.017 among normal haplotypes from Jews. Of the remaining DR4-positive patients, all but one had a presumed D-region segment (defined as SC21, DR4, DQw8 or SC31, DR4, DQw8 with variable HLA-B) of these haplotypes. Only one patient had DR4, DQw8 without any other markers of the extended haplotypes. The number of homozygotes and heterozygotes for DR4, DQw8 was consistent with dominant but not recessive (P less than 0.01) inheritance of a class II or a class II-linked susceptibility gene for the disease. Since the disease is entirely attributable to the presence of an antibody to an intraepidermal intercellular cement substance, it is likely that the class II susceptibility gene (on [HLA-B38, SC21, DR4, DQw8], HLA-B35, SC31, DR4, DQw8, or their segments, in Jewish patients) controls the production of the antibody as a dominantly expressed immune response gene.

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=54807

It doesn't affect progeria or shortening of telomeres but I am suggesting that if you look at all the factors that are affected during ageing, there may be one factor that will caue age to elongate - e.g. a restricted calorie intake. I think I have read that restricted calorie intake contributed to the delayed senescence of laboratory animals but someone would have to find a suitable reference for me.

Progeria seems to be due to accelerated ageing and I wondered if an elucidation of the molecular processes taking place in accelerated ageing could be slowed down to decrease ageing in others. I know this is simplistic but in the factors that affect ageing, I am sure that all do not have an equal bearing on the ageing processes.

HGPS is caused by a mutation in the gene called LMNA (pronounced, lamin - a). The LMNA gene produces the Lamin A protein, which is the structural scaffolding that holds the nucleus of a cell together. Researchers now believe that the defective Lamin A protein makes the nucleus unstable. That cellular instability appears to lead to the process of premature aging in Progeria.

http://www.progeriaresearch.org/about_progeria.html

http://commons.wikimedia.org/wiki/File:Hutchinson-Gilford_Progeria_Syndrome.png