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Dagl1

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Everything posted by Dagl1

  1. But in the case of boxing, the people doing the boxing aren't the only ones at risk, as they will have to be cared for by society eventually due to the potential damage they have accumulated over the years. So in that case, do we have a moral right to ban to thereby reduce the burden on people who aren't taking that risk?
  2. Dagl1

    Plasmid delivery

    Alright I see; so you want to transmit some DNA to bacteria present within the human body (and this DNA should not be detected as to not destroy it through immune defences I presume) which then should produce a protein inside those bacteria. As Charon said previously, researchers have used several small molecule / nano containers for drug delivery, you may be interested in reading further into nano-containers: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5636659/ . One other thing is to make sure that if your target for protein production are bacteria and not humans, you have to choose the right promoter etc. At university I once had to give a presentation about polymer nanocontainers, and while looking back at the presentation its pretty bad, but here are some references used: These are mostly regarding drug delivery http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322773/ https://www.ncbi.nlm.nih.gov/pubmed/20394391 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626985/ https://www.ncbi.nlm.nih.gov/pubmed/19825408 For gene therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449975/ https://www.sciencedirect.com/science/article/pii/B9780081005576000043 https://www.ncbi.nlm.nih.gov/pubmed/19488722 However, of course these methods are mainly for eukaryotic cells, I think exogenous RNA/DNA delivery into bacteria present within the body is something not researched very much.
  3. Dagl1

    Plasmid delivery

    @CharonYIs it possible to, as OP is asking, provide a protein-encoding plasmid that is immuno-invisible? I feel like it shouldn't as that protein could always become an antigen for T cells to present right? Edit: OP isn't specifically asking for a protein-encoding plasmid, but I could see how non-coding plasmids could be immuno-invisible, so the question is mostly interesting when talking about protein-encoding plasmids
  4. Hmm personally I lean towards allowing it if no one is forced and everyone is like Prometheus says, but for me more importantly would be consistency: If boxing would be banned, american football and rugby maybe as well should be banned and I feel like then possibly alcohol should also be banned. If other people are not allowed to practice a sport they enjoy for their own entertainment and that of others, while acknowledging the risks, then i feel that should apply to alcohol and all things in life. But as I said, I lean to allowing most things and just letting people deal with the consequences (if people are adequately warned and have some sort of choice (not in the free-will sense but just general common language), but if we do decide to ban sports like boxing, then please lets go all the way and be consistent.
  5. The ones I am using and haven't thought too much about would be: Knowledge; information known by any intelligent species or recorded/accessible by any intelligent species. (Def. of intelligent species in THIS particular case; any species capable of storing information or passing on information in a manner that is not sheer luck (and leads to technology? I don't know how to exclude bacteria and animals capable of carrying genetic information across generations in their epigenetic markers.) Value of knowledge; the value of knowledge lies in the potential benefits that come from changes motivated by knowledge Gotta be honest, I am not 100% attached to these definitions, but feel like I should at least give it a try, I am open to other more inclusive/exclusive definitions
  6. Ye I okay, I see your point and in response my view is now: While engaging in metaphysics can be interesting and one can use thoughtful analysis and apply logic to these questions, but whatever answer is accepted by everyone, can never be validated or falsified right? I think that's why before I used speculation, but I do see how that term is stigmatised. To me, anything that cannot be validated or tested, that is added to our shared knowledge, doesn't add much value, whereas science can be falsified and its effects can be seen/experienced (inventions/technology). Although I can see discussion regarding morality (if that is in the realm of metaphysics), moral frameworks and potentially a consensus on 1 specific moral framework that everyone believes in, to definitely have effect on our reality, but through the actions of people. But as you said, engaging in metaphysics happens quite fast and can be interesting, so my initial view definitely was too negative and ignorant of it. -Dagl
  7. So would you say that this model has evidence supporting it that other models don't have, or is this model just a different way of expressing particular formulas (aka, nothing changes just a different interpretation)? Or are there specific moments/scenarios where using this model is easier or more accurate than other models?
  8. @Strange So I am wondering, are you saying that metaphysics isn't speculation about unknowable (I suppose that isn't what mistermack said exactly, so maybe I am putting words in you mouth) things? As far as I can see (but I am not well studied here so I might be wrong), metaphysics discusses stuff that by its very nature cannot be determined. If something could be predicted, measured or modelled, it would be within the realm of science/physics and not metaphysics. If at some point the entire metaphysical community agrees on a theory/hypothesis of reality, it will not change anything in reality right, nor will having it wrong or right (if that is even possible) make a difference as anything that has effects on the physical world, will immediately not be part of metaphysics. Anyone has any thoughts or comments?
  9. So what does this model explain or predict that other models fail to and do these predictions match with what we measure, are there even measurements or predictions that would make it possible to falsify this model?
  10. Just a follow up question; is the mass that I observe of an object (when at rest near each other they all have the same mass), going with 90% the speed of light towards me or with 20% the speed of light away from me, different?
  11. Yes, so one would get 2 diagonal beams right (if you would have a screen after it), if now we place another 2 slits in the path of 1 of those beams, do we get another interference pattern from that second double slit?
  12. Even when observing which slit a photon goes through (then I suppose those experiments aren't done with photons but electrons or other mass-carrying particles?)
  13. It seems like you are saying that without a plate or screen there is no interference pattern? and I assumed in an experiment one would shoot many electrons (or photons) after each other so they can only interfere with themselves (that is one of the things the double slit experiment shows right?). In case you need a plate or screen at the end, I fail to see how this works, but is this in the same realm as the delayed quantum choice experiment? I will have to rewatch that as well I suppose.
  14. Ye will do, I also realise that I should, just like many here are recommended, understand the math behind this stuff, so I suppose I will be taking a look at the "scary" part of physics;p
  15. After reading the thread again, I think I didn't absorb the information that much yesterday, but also realise this goes a little over my head for now. So @studiot regarding your first message; I now understand the issue regarding planar vs spherical waves, so (please correct me if I am wrong) at first the wavefunction is only expanding "forward" (again my apologies for the lack of the right terminology, I don't know if either "expanding" or "forward" or the right words to use) towards the slits, but afterwards is expanding like a sound wave would, but that would only happen if there is no measurement at the first slits (in the double slit experiment, if we observe through which slit the wave travelled through, we see 2 lines instead of an interference pattern, right?)? But if we do no measurement, placing new slits after the first slit would not capture all of the spherical wavefunction (thereby completing changing the experiment)? For my understanding, if I would, lets say put a doubleslit at x distance (lets say, 5, 10 or 15cm away), so that the new slits are directly in the path of light that goes through 1 of the slits. What kind of pattern (at all) would a screen behind this second pair of slits capture, if we have observed/measured at the first slits. And this is in a perfect vacuum with as little interference as possible from radiation(and whatever else is needed for such a thing to experimentally work). My thought process: As we observe the wavefunction at the first slits, we would expect the waves to produce 2 straight lines, so the wavefunctions are still travelling in a straight line, and have not become an interference pattern, so from the perspective of the second slits, this is just the light that has gone through 1 of the slits and since we aren't measuring here, I expect that this would then produce a normal interference pattern. But only if the wavefunction is not collapsed anymore because of the measurement at the first slits, so I was wondering, how would such a wavefunction "re-form" the state of superpositions in the time traveling to the next slit? I hope there is at least some part of this stuff that I understand, but I realise most of my assumptions or thought process will most likely be wrong or just filling in information, so thank you all for your help! -Dagl
  16. Alright so it seems my question boils down to: how does the particle/wave function form new superpositions, and what determines the time frame before this happens?
  17. Can photons or other particles form a wave-function again after an "observation" or "measurement" and what determines when or how that happens. So for example, we attempt the double slit experiment, where we have a measurement device at/before the slits, and have thus collapsed the wave-function, leading to 2 lines and not an interference pattern. So if we put the screen further away, then add new splits, would we at some see an interference pattern again? I hope that my question itself is clear, in case there are technical reasons why my above experiment wouldn't work. Thanks!
  18. The upper part of my post was mostly a sort of copy-paste reply to ag400002, I don't think it is the most important question, however wouldn't you agree that physics does give some description or characteristics to time through space-time/relativity, CPT symmetry (or lack thereof), thermodynamics and probably many more fields/subjects that you are way more familiar with than I am;p I feel this is still within the realm of physics than metaphysics, but maybe it is the semantics of the question "what is".
  19. Perhaps the deepest mystery in physics is "what is time" And while we, as far as I understand, have concepts of time in both space-time and thermodynamics, Perhaps the reason it is so, is that pseudoscience and philosophy can never unravel this question, because their cultures and internal disciplines too readily turn their back on real measurement and theoretical modelling, where the answer is, resulting in too many people on our planet drowning and floundering in a quagmire of wild ideas, speculation and posts with many substantial claims and 0 evidence or references given. I really like this quote: "The conquest of nature is to be achieved through number and measure." Math is, for whatever reason reality follows these rules, the tool with which science attempts to explain reality. It is so far the most successful method,. That doesn't mean philosophy has no value (as I can see that my post may insinuate that), but that its value is not as great in the quantitative sciences as true understanding of mathematical models is. -Dagl
  20. One thing regarding (some forms of) phage therapy is that they negatively effect the immune system in research studies. While a phage may combat a specific bacterium, the bodies reaction to the increased viral load (if I remember correctly) leads to either overreaction of the immune system or increased infection risk to new pathogens. (I currently don't have the papers in front of me, if someone wants them I'll look them or similar ones up). Charon, some time ago I read these 2 papers (and some of their references) regarding acquisition of antibiotic resistance, which I believe goes counter to consensus, but I am not very read in this field except for papers from this "group", so I have a very biased view of this at the moment. I was wondering if you can comment on these papers, specifically on any statements related to: "Most of us were taught that terminating antibiotics prematurely can lead to the development of bacterial resistance. This has proven to be a myth as mounting evidence supports the opposite. In fact, it is prolonged exposure to antibiotics that provides the selective pressure to drive antimicrobial resistance; hence, longer courses are more likely to result in the emergence of resistant bacteria.14,15 " https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661683/#bibr14-1715163517735549 This article is the main driving point as far as I remember when reading about these papers, but can't access it at the moment. I really like their comment/peer review section, interesting to hear about the opinions of many in different fields. https://www.bmj.com/content/358/bmj.j3418
  21. I think a lot of people have heard this, as it was the primary hypothesis, but from this PBS space time video (see below) and some other sources, it seems that novae are less of a contributor to the overall heavy element makeup and instead neutron stars are now the main culprits. Would like to note that I am not very researched in this field, I have just watched some videos and read some basic stuff about it, my apologies if those sources are incorrect or are presenting the change in hypothesis as something that has found consensus in the community when this may not be the case. -Dagl
  22. Except for the unusual usage of "ambassador" RNA for mRNA, I would like to add that RNA can be divided into many many more types (eRNA, microRNA, snoRNA, uaRNA, ptRNA, piwi-interacting RNA, and the larger non coding RNAs). So what would you like to discuss? Or do you have questions, as based on your other post, where you discussed both heterogeneous and homogeneous alleles and a thing called Zarah, it seems you have a skewed idea of biology and questions may be more useful for you than to only post information. -Dagl
  23. I cannot put into words the dread I feel sometimes. I'll try though. holy fuck
  24. Some SCP's are written much better than others (the benefit and disadvantage of having many writers that can all submit their work). I know that Laphroaig is a drink, but I am really not getting it;p are we comparing rules in language with alcoholism or something like that??
  25. @strange SCP is a wonderful community written fictional universe, where things are written as SCP-xxxx articles (as if researchers write about SCP's in-universe). SCP stands for secure, contain, protect. And each SCP is an anomalous object, with specific containment procedures and lore behind it. It remains strange that clear rules are not present for such (grammar) things, but I suppose it is the same as for adjective order; wooden blue big table sounds strange, big blue wooden table does not (IMO) (there are only guidelines for adjective order as far as I know).
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