tkadm30

Whatever medicinal effects it may have, it does not support your recreational use of it, which, I think, is your ulterior motivation for banging on about it... and other people as well.

This thread is about the potential anti-cancer effect of cannabis. Your comments are evidences of your utter ignorance on the subject.

Oh dear, I'm sorry to hear you had a negative experience with weed. But since this is a science forum, your personal experience is irrelevant to the supporting evidences that cannabis can have a dramatic effect on cancer.

 

Indeed. Smoking cannabis is only good for polluting the lungs.

I disagree. Cannabis has many medicinal properties and can potentially be used to treat brain cancer.

Furthermore, marijuana smoking actually improves lung function: http://jamanetwork.com/journals/jama/fullarticle/1104848

I suggest you stop talking nonsense...

 

Could you kindly list which of the mentioned authors were funded by pharma companies?

Curran et al Nat Rev Neurosci (GlaxoSmithKline)

Skosnik et al. Biol Psychiatry (Pfizer)

Note also that most studies you cited were not open access...

Since the brain of a children isn't fully mature, imagination is probably essential to the development of the brain.

THC kills cancer cells in vitro and in vivo.

 

Several preclinical studies suggest that Δ⁹-THC, other naturally occurring cannabinoids, synthetic cannabinoid agonists and endocannabinoids have anti-cancer effects in vitro against lung carcinoma, gliomas, thyroid epithelioma, lymphoma, skin carcinoma, uterine carcinoma, breast cancer, prostate carcinoma, pancreatic cancer and neuroblastoma [4]. These findings were also supported by in vivo studies and the majority of effects of cannabinoids are mediated via CB1 and CB2.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171598/

Here you go:

https://scholar.google.ca/scholar?hl=fr&q=aluminium+oxide+alzheimer&btnG=&lr=

https://scholar.google.ca/scholar?q=aluminium+oxide+amyloid&btnG=&hl=fr&as_sdt=0%2C5

Do not forget that many of theses studies were funded exclusively by pharmaceutical companies also selling synthetic drugs for schizophrenia. The political lobby and government-sponsored research on schizophrenia is a much more lucrative business than cannabis research. Fortunately, I hope the global legalization of marijuana will correct this by financing novel research on the medical applications of cannabis.

Another poorly understood regulator of creativity is dopamine neurotransmission. Dopamine and neuregulin-1 are promoters of gamma oscillations in the hippocampus, a key organ in the regulation of creativity and synaptic plasticity.

iNow, I do agree with you. However, please understand that the neuroscience of creativity is complex and that synaptic plasticity is probably correlated. You should as a minimum take a minute to consider this fully.

I caught a cold from my co worker, is that considered a bio weapon, I was sick for three days. What other types of bio weapons are there?

Viruses can be effective vectors in biological warfare: The recent engineering of the Influenza A/H5N1 supervirus is a potential bioweapon.

Personally, I prefer feeling happy rather than full of fear.

Your search results do not support your claim. The neuroscience of creativity overlaps with the study of synaptic plasticity, but your conflation of them is why you're mistaken. They are not the same thing and the neuroscience of creativity is NOT best known as synaptic plasticity. Stop talking bollocks.

OK. Let's just assume that synaptic plasticity is implicated in the neuroscience of creativity.

And in case you missed it, Neuregulin 1 is a gene related to creativity AND synaptic plasticity.

"Best known" and "found ONE research paper." Perhaps you see the flaw in your argument?

Actually, a search on google scholar produced 21100 results.

Furthermore, the gene Neuregulin 1 (NRG1) appears implicated in the neuroscience of creativity and psychosis: There's supporting evidences that this gene polymorphism is connected to prefrontal synaptic plasticity and schizophrenia.

Why is aripiprazole (Abilify) considered a third-generation atypical antipsychotic?

Your question is?

If antipsychotics enhances AKT1 signaling, does it increases THC tolerance ?

It appears the role of the AKT1 genotype has been implicated in THC tolerance.

Interestingly, delta9-tetrahydrocannabinol (THC) may activate the AKT1 gene in vitro and in vivo. This pharmacological activation of the AKT1 gene by THC might explain why THC administration is neuroprotective in Alzheimer's disease.

I think scientific imagination require a good dose of creativity to create experimental theories; To think like a scientist does not imply to ignore imagination for representing reality...

It's not. Those are distinct topics.

Well, I found at least one research paper to support my claim.

Actually, the dreaming brain appears and behaves much like that of a schizophrenic, which are both prominently characterized by low prefrontal activation (hypofrontality). However, the specifics of what causes this low prefrontal activation between the dreaming and schizophrenic brain may be distinct.

It is important to note that this phenomenon is termed "transient" hypofrontality: https://www.ncbi.nlm.nih.gov/pubmed/12763007

Sleep related hallucinations are usually hypnagogic or hypnopompic.

They are a parasomnia and totally unrelated to schizophrenia. http://www.sleepeducation.org/sleep-disorders-by-category/parasomnias/sleep-hallucinations/overview-facts

I believe the neuroscience of creativity is best known as synaptic plasticity.

Thanks guys. I don't mean to have higher creativity skills, but that imagination flows together with experimentation. I might be learning the scientific method the hard way by studying Arts, but I find the connections between art and science highly relevant in creating experimental theories.

Scientific imagination is critical to develop new theories based on the evidences of the beauty of nature. It is an artistic talent to recognize the capacity of the mind to illustrate scientific discoveries into abstract models through experimentation and observation. The artistic value of an "experimentation" should be defined as the mind power (creativity) to understand the logicality of nature.

This paper might be relevant to the OP. Also note that enhanced dopamine neurotransmission during meditation may increase noradrenergic releases in the prefrontal cortex (PFC). https://www.ncbi.nlm.nih.gov/pubmed/18615131

Neuronal phase coherence is "quantum-like" because long-range synchronicity is critical for optimal communication

in the gamma band.