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The use if siRNA itself to knock down genes is universal and been discussed as an antiviral for quite some time. The tricky bit is the delivery to target sites. In this case, they took advantage of the fact that certain lipid nanoparticle compositions have been shown earlier to accumulate in lungs, so when delivered intravenously they were able enrich the siRNA in lung tissues. For other tissues and cell targets (which include HIV) it may be more difficult to deliver the siRNA there. Difficult to tell, normally they need a controlled trial on humans first to make sure that it is safe. One issue of the paper is the use of a mouse model, which might have rather different results than in humans. The target of SARS-CoV-2 spike protein is the ACE2 protein, but the one in mice is sufficiently different to have reduced binding efficiency. Folks have expressed human ACE2 in mice (and the authors of the paper used such a mouse line) to improve their use as model. While on the symptomatic side they are closer to human infections than the wildtype mice, the transgenic mouse line has a few issues which and differences, which makes transferring treatments directly to humans without trials quite difficult. However, there are other therapeutics in play, such as Plitidepsin which are already in trials (Phase 3) and have been established in similar animal models.

Disproof already done by other members. Are these the "gongs"? What evidence supports your hypothesis? As far as I know mainstream science says the structure is a djed. Wikimedia has various pictures of Djed hieroglyph and amulets: https://commons.wikimedia.org/wiki/Category:Djed_(hieroglyph) Example:

When I was a young bloke, I was walking/waddling home early one morning [about 0200hrs] after a night out on the piss. Walking up my drive way i walked into a spiders web, and in my efforts to shake off any spider [I forgot to mention, I hate spiders and creepy crawlies] woke the neighbourhood up with my screams and swearing and jumping up and down, for them to see a pissed, half naked man. Not sure I would have acted any different even if sober! 😛

I was going to get my mail a couple days ago and a couple misguided youths had placed a (very realistic) rubber rattlesnake in the sidewalk to the mailboxes. They rolled out of a car across the parking lots reveling in laughter saying "you might be white headed but you still have the moves!" I must admit I found a few old moves real fast.

If the Earth was the size of a tennis ball, this video explains the size and scale of the universe. This video will make you feel very small.

I visualise the observable universe size - 96BLYRS - this way: if the diameter of our galaxy is 1mm, the universe is 960m across.

Was this item the only one made of this "slate", or were other objects made of it as well? And was it really slate, or could it have been siltstone? Real slate flakes easily into layers and is not ideal for carving, whereas siltstone is much more suitable. I quote an extract from the Wikipedia article on the Narmer Palette, which was thought to be made of slate but is actually siltstone. The Narmer Palette is a 63-centimetre-tall (2.07 ft), shield-shaped, ceremonial palette, carved from a single piece of flat, soft dark gray-green siltstone. The stone has often been wrongly identified, in the past, as being slate or schist. Slate is layered and prone to flaking, and schist is a metamorphic rock containing large, randomly distributed mineral grains. Both are unlike the finely grained, hard, flake-resistant siltstone, whose source is from a well-attested quarry that has been used since pre-dynastic times at Wadi Hammamat.[13] This material was used extensively during the pre-dynastic period for creating such palettes and also was used as a source for Old Kingdom statuary. A statue of the 2nd dynasty pharaoh Khasekhemwy, found in the same complex as the Narmer Palette at Hierakonpolis, also was made of this material.[1 From: https://en.wikipedia.org/wiki/Narmer_Palette

Yes, keep discussing thinks this is progress i can feel it good job everyone. We are going somewere now. @swansont If your degree teaches you to sensor youtube video's on a science forum than that is money well spend my new online friend. (I am from Holland not Russia) i am not used to being censored. Tanks a lot for opening my eye's that was a good experiment now please go back to the topic.

Nice this is good, come on keep this spirit up. My Dutch translation that is presented with the object in question is Leisteen (that is slate in English) and this is the only information presented with the object that could have been seen in the video if the link to it was not removed!!! The object in question the; gong/disk can bee found in the National Museum of Antiquities addres: Rapenburg 28, 2311 EW Leiden, Netherlands It is the only one of its kind left. As you mentioned, it is fragile and is prone to flaking. Again where this object is located is in the video!!! Just save us some time and publish the link to the video, there is more info there. Make a special exception for dyslectic people or something. Evermind i found it!!! You can see the video URL via the link presented in my profile information. Bypassing the no posting video rule of this homework tread for students.

Great you found something cool now i did not see this one before but it look like its osiris and isis and in between a thing (just like the djed) that has arms and a circle above it. Amazing job, i will explain it to you: the circle represent the invisible radon gass just like i have explained in my video description. (I had forgotten to put it in the video) Please explain how you draw that conclusion from my comments I am not going to teach you ancient knowlage here on this platform i don't like how the censorship is managed. If you could message me personally, i could try my best.

Fun fact: the piramids do not have 4 sides but 8 If you did not know this already, think about how smart they were before you got interested in the ancient Egyptians. And dubble that of how smart you thought they were by a factor of 2. SO stop trying to be smart with you little calculations and your fancy degrees because we do not understand shit!!! @ robincook Tip: put your webside url in your profile info.