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How to dissolve EDTA? Rate Topic: -----

#1 5 April 2009 - 09:11 AM peacefulspring 


Lepton
Hi,
can anyone tell me how to dissolve EDTA with acid and alkaline with the concentration of the reagents also. Thanks.
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#2 5 April 2009 - 10:49 AM Kaeroll 


Baryon
Unfortunately I don't have access to belstein from home, or I'd look it up for you. I imagine EDTA is reasonably soluble at neutral pH, but you could use pKa values to work out a pH at which it will be charged and buffer your solution to that.

Alternatively, figure it out experimentally. Put some EDTA in a beaker with water (I assume that's the solvent you're using) and see how pH affects solubility.
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#3 6 April 2009 - 12:09 AM CharonY 


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Biology Expert
Generally EDTA dissolves OKish at high pH (around 8). I think you may get up to 0.5 M then. At near neutral you would only get a couple of mM into solution (I think around 10, but I may be wrong).
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