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as regards the legacy of N-genes in caucasoids i will keep an open-and-infantile mind.
don't all hypotheses have holes in them?
i am, like you, in two minds about the mitochondrial data. i think your criticism of how this data is interpreted is valid. it is considerably easier to isolate sufficient amounts of intact mitochondrial DNA for sequence analysis compared to genomic DNA, this practical point biases the data - nevermind the interpretation of the data. likewise, the considerable paucity of data and difficulty, more ethical than technical, of performing hybridization expts in mammals also creates a bias.
can anyone think of any expts which would overwhelmingly demonstrate the legacy of N-genes in caucasoids? the reason i ask this question is that i am most curious about whether it is in our ability as scientists to find an answer.
one day someone may recreate germ cells from N-man and N-woman and see if they can fertilise or be fertilised. however even if this was done, it wouldn't be the final experiment because there are a range of immunological factors that determine fertility in vivo and also they wouldn't measure the survival fitness of the offspring. there are more obvious experiments i could think of, but these would be flawed too.
I am excited with new genetic techniques that are coming along. I am sure they can aid in the discovery of the genes I believe to exist in the caucasoid gene pool.
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can anyone think of any expts which would overwhelmingly demonstrate the legacy of N-genes in caucasoids?
I believe all the physical evidence before us is overwhelming in my eyes. As you mentioned, which I took as an insult before thinking it over, we need to keep an infantile mind in some degrees. Often major scientific discoveries were made by people who have untainted open minds about new scientific ideas. I am trying to deduce my hypothesis (and the hypothesis of others) based on raw physical evidence. Although its a semi-flawed way to create an assumption, I think the evidence is pretty logical to a large degree. As mentioned before, assuming that the out of Africa theory is correct, I find it perticularly odd that such a young race as caucasoids are (30,000-40,000 years old) have adapted so well to there cold enviroment compared to the mongoloids (60,000-possibly 120,000 year old) who have been in a cold enviroment for a much longer period of time.
In fact, I dare say that other than superficial differences like shape of eyes, mongoloids have only adapted the white skin for a colder environment. Mongoloids still have dark hair and eyes, broad negroid noses, and a slender frame. This is very consistent with there Negroid ancestors. Caucasoids exhibit strikingly cold adapted features, the extreme case being of course the ginger gene, which produces orange hair, green eyes and freckly skin. Thus it is my assumption by deductive logic that Caucasoids inherited a genetic legacy from Neanderthals, thus giving them a "boost" in cold adaptation over there mongoloid and negroid ancestors.
But in the end of course, whats overwhelming evidence to one (me), could be a brush off evidence to another (Milken perhaps?). So evidence itself is all subjectional. One thing is certain, with time we will certainly know the true answer, that I am personally certain of.
Moonquake said:
So they remained side by side for 6000-10000 years and remained two completely distinct types of homonid for all this time dispite being able to interbreed?
Well the debate is if it were possible to interbreed. With current genetic techniques we cannot tell if a hybrid could be produced, at least a fertile one. But it is my reasoning as presented above that it was highly possible, almost a certainty that a few hybrids were produced who then were able to pass on some of the Neanderthal genetic legacy into the local gene pool which then seeped into the greater Caucasoid gene pool over time.
Edit: I just thought of one more thing... this of course means nothing unless you want it to though. Neanderthals reigned from 200,000 to 30,000 years ago. Homo Sapien left Africa roughly 160,000 years ago. Sapien arrived in Europe around 40,000 years ago. Sapiens and Neanderthals branched off from a common ancestor roughly 200-250,000 years ago. Lets do the math. Neanderthals had no contact with there direct sapien cousins for about 150,000 years estimated. On that same note, Negroid Sapiens have not had contact with there descendants from most other gene pools for roughly that same amount of time, and in many degrees if you look at pure blooded Africans and pure blooded Native Americans for instance, you see the same amount of time has passed between potential sexual contact as has passed between sapiens and neanderthals. But oddly enough, a Negroid from Africa can reproduce perfectly healthy and fertile offspring with a Native American with just as much success as a Negroid with a Negroid, or a Native American with another Native American.
In conclusion, Negroids have been out of sexual contact with other Sapien gene pools just as long as Neanderthals were out of contact with there African cousins. Yet we make the assumption that Neaderthals and Sapiens could not have interbred even though Negroids can produce viable offspring with any of there descendents to this day.