Jump to content

Clinical trial challenges


charlotte17

Recommended Posts

Does anyone know of any challenges related to clinic trial of pharmacotherapies particular in phase 2 and 3?

 

I have bio - availability, plasma half-life, compliance and side effects. Not sure which would fit where though.

Link to comment
Share on other sites

Compliance seems rather a challenge of phase 3 and 4 studies; to a lesser degree phase 2.

 

Bioavailability, plasma half-life would seem phase 2 to me, and side-effects actually phase 1 or 2: some side-effects may already be observed in a preclinical phase in laboratory animals.

 

Efficacy is typically phase 3, whereas efficiency (cost-effectiveness) applies to phase 4 studies ...

 

Of course, the degree to which you may or may not extrapolate your results is a huge problem in phase 2 and 3 studies.

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...

Important Information

We have placed cookies on your device to help make this website better. You can adjust your cookie settings, otherwise we'll assume you're okay to continue.